IL-17F-induced IL-11 release in bronchial epithelial cells via MSK1-CREB pathway

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IL-17F-induced IL-11 release in bronchial epithelial cells via MSK1-CREB pathway.

IL-17F is involved in asthma, but its biological function and signaling pathway have not been fully elucidated. IL-11 is clearly expressed in the airway of patients with allergic airway diseases such as asthma and plays an important role in airway remodeling and inflammation. Therefore, we investigated the expression of IL-11 by IL-17F in bronchial epithelial cells. Bronchial epithelial cells w...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology

سال: 2009

ISSN: 1040-0605,1522-1504

DOI: 10.1152/ajplung.90607.2008